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Choose from exclusive hotel collection
We offer thousands of Panama City hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.
Enjoy seamless booking experience
Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.
Benefit from flexible travel options
We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.
Welcome to Panama City
Explore the vibrant and cosmopolitan Panama City! With its modern skyline, colonial architecture, mouth-watering cuisine, and friendly locals, this Central American gem attracts visitors from all around the world. Be sure to check out the Panama Canal, Casco Viejo, and Ancon Hill for unforgettable experiences. Don't wait, book your trip to Panama City today for an unforgettable adventure!
What our users say about Panama City hotels
The accommodation is pet-friendly, well-equipped with spacious private bathrooms, and provides efficient service, even though some staff members may not be very helpful.
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The hotel was hip new, had stunningly beautiful views and perfect location close to a water park and near by attractions and the center. I appreciated the room, the bed was comfy. There were a flat-screen TV with cable channels, climate control and a refrigerator. The staff was excellent, they made the stay good.
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Thanks very much all for an awesome stay during our visit.
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The rooms and the staff here are top-notch. We were impressed by almost every little thing at this place! 😊
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The great location within walking distance of Alvin's Island and the luxurious room with extremely comfortable beds make this place a top choice for a relaxing stay.
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The rooms were clean and had a fantastic bathroom, located in a beautiful building in a convenient area close to the Bistro.
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I had a wonderful family vacation here, the staff was great, the rooms were nice, and the bed was super comfortable.
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Everything was perfect here - helpful staff and non-smoking rooms.
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The location was amazing, very close to Universal Studios, liquor stores, parks, restaurants.
It was not too far from Trattoria del Porto; we ate there a couple of times.
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Decent spot, quite tidy and cool. Liked it. Room was pretty clean and had a good view. 🌅
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Save time on your trip arrangements by booking one of our hand-picked hotels
Top 5-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Indulge yourself with luxury and comfort as you explore the exciting attractions of Panama City.
Enjoy truly authentic experiences without compromising comfort and convenience.
- Best Western Plus Panama City Hotel
- Hotel Indigo - Panama City Marina By Ihg
- Days Inn By Wyndham Panama City
- Comfort Suites Panama City Near Tyndall Afb
- Holiday Inn Panama City By Ihg
- Comfort Inn & Suites Panama City North
- Courtyard By Marriott Panama City
- Hilton Garden Inn Panama City
- Towneplace Suites By Marriott Panama City
- Emerald Beach Resort By Resort Collection
- Raven Beach House Hotel
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Discover the hidden gems of Panama City by booking one of its budget-friendly hotels.
- Suburban Studios Near Panama City Beach
- Hathaway Inn
- Rodeway Inn Panama City
- Baymont By Wyndham Panama City Beach
- Candlewood Suites Panama City - Tyndall Afb By Ihg
- American Quality Lodge
- Super 8 By Wyndham Panama City
- Quality Inn & Suites Near Panama City Beach
- Days Inn By Wyndham Panama City/Callaway
- Holiday Inn Express Hotel & Suites Panama City-Tyndall
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Travelers’ choice
Check out the most booked accommodations to find reliable places that our users have tried and tested.
- 3 Bedroom Catalina Townhome With Rooftop Deck Great Oceanviews, Steps To Beach
- Charming 3-Bedroom Home In Beautiful Panama City
- Luxury Bathroom Home With Game Room 25 Mins To Pcb
- Panama City Home With Beach Gear And 2 Bikes
- Escape To Paradise W Saltwater Pool 25 Min To Pcb
- Dreami Stays Panama City - 2Br Retreat Near Downtown, Beaches, & Hot Spots
- A Block Away From Beach/Harbor/Fine Restaurants
- Sunny Panama City Escape With Pool And Deck!
- Adorable 1 Bdr With Full Kitchen Deck Washer Dryer
- Pc Poolside Palms Apartment
- The Splash Pad Sleeps 13 W Pool Patio And Garage
- Stylish 3Br 2Ba House Minutes From Pcb - Book Now Villa
- Luxe Pool Casita W Saltwater Pool 25 Min To Pcb Apartment
- 6 Bedroom Townhouse With Rooftop Deck Great Oceanviews 6Th Br Is Detached
- South Walton Condos II
- Quiet Coastal Retreat On Pcbs West End
- Regency Towers 1122 'Seas The Day' Villa
- Ocean Spray Villa
- Quick Commute To Hospitals And Tyndall Gorgeous Stay
- Waterfront 1-Bedroom Condo In Panama City
- Destin Towers 1E Apartment
- Aquamarine Dream Deluxe, Sleeps 6, Free Parking! Villa
- Charming 3Br Home With Free Parking & Game Room
- Renovated Townhome By The Bay
- Lakefront Panama City Studio With Hot Tub Access
- Two Spaces In One Main House And Guest House 25 Min To Pcb
- Spacious 3-Story Bayfront Home Perfect For Family Fun & Relaxation
- Canalfront 3Br Near Panama City Beach Duplex
- 13 Mi To St Andrews State Park Cabin With Patio!
- Blue Tide Hideaway - Golf Cart, Sznl Hot Tub, Pets Ok, Free Daily Activities, & More!
- Laid-Back - Private Pool, 4 Min Walk To Beach, Close To 30A, Free Daily Activities
- Lux Min To Beach And Hospital With Hot Tub
- Beach House With Private Pool - Sunny Sands By Panhandle Getaways
- Luxe Guest Suite Near The Emerald Coast Of Pcb
- Sunshine House! 3Br 2Ba Sleeps 9! Your Perfect Retreat For Comfort And Style
- Pinnacle Port Penthouse 10
- New Spacious 3Rd Fl Patio And Bar With Costal View
- Down By The Bay W Hot Tub, 2 Blocks 2 Beaches, Game Room, Reading Nook, Dog-Friendly, Historic Charm
- Beautiful House In Panama City
- Salt Water Pool, Game Room, King Bed &Pet Friendly
- 7 Mi To Dtwn Panama City Family Home With Patio
- Loaded House And Guest House W Game Room Gym
- 17 Trigger Trail West Villa
- Cozy 4Br Panama City Retreat! Games & Beach Gear!
- A Love Of Leisure
- Lovely Panama City Cottage Walk To Bayside Beach!
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