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Choose from exclusive hotel collection
We offer thousands of Port St. Lucie hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.
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Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.
Benefit from flexible travel options
We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.
Welcome to Port St. Lucie
Port St. Lucie is a flourishing city set in the heart of Florida's Treasure Coast. Known for its pristine golf courses, fine dining, and a plethora of outdoor activities, Port St. Lucie has something for everyone. Bask under the Florida sun on its breathtaking beaches or visit its beautiful parks. Ready to explore? Come experience the charm of Port St. Lucie for yourself!
What our users say about Port St. Lucie hotels
The accommodation is pet-friendly, well-equipped with spacious private bathrooms, and provides efficient service, even though some staff members may not be very helpful.
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The hotel was hip new, had stunningly beautiful views and perfect location close to a water park and near by attractions and the center. I appreciated the room, the bed was comfy. There were a flat-screen TV with cable channels, climate control and a refrigerator. The staff was excellent, they made the stay good.
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Thanks very much all for an awesome stay during our visit.
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The rooms and the staff here are top-notch. We were impressed by almost every little thing at this place! 😊
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The great location within walking distance of Alvin's Island and the luxurious room with extremely comfortable beds make this place a top choice for a relaxing stay.
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The rooms were clean and had a fantastic bathroom, located in a beautiful building in a convenient area close to the Bistro.
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I had a wonderful family vacation here, the staff was great, the rooms were nice, and the bed was super comfortable.
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Everything was perfect here - helpful staff and non-smoking rooms.
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The location was amazing, very close to Universal Studios, liquor stores, parks, restaurants.
It was not too far from Trattoria del Porto; we ate there a couple of times.
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Decent spot, quite tidy and cool. Liked it. Room was pretty clean and had a good view. 🌅
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Save time on your trip arrangements by booking one of our hand-picked hotels
Top 5-star hotels
Best 4-star hotels
Exclusive 3-star hotels
Indulge yourself with luxury and comfort as you explore the exciting attractions of Port St. Lucie.
Experience the best value for your money by checking out our selection of 4-star Port St. Lucie hotels.
Enjoy truly authentic experiences without compromising comfort and convenience.
- Best Western Port St. Lucie
- Sleep Inn Port St Lucie At Pga Village
- Homewood Suites Port Saint Lucie-Tradition
- Holiday Inn Port St. Lucie By Ihg
- Towneplace Suites Port St. Lucie I-95
- Courtyard By Marriott Port St. Lucie Tradition
- Residence Inn Port St Lucie
- Maria'S Bed And Breakfast
- Mainstay Suites At Pga Village
- Carols Palm Hotel
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Travelers’ choice
Check out the most booked accommodations to find reliable places that our users have tried and tested.
- A Treasure Coast Gem- Private Entrance And Private Bathroom
- Gallery Suite Tropical Retreat Pool Access
- A Family Place For You
- Backyard Oasis Villa
- A+ Bnb
- Port St Lucie Canal-Front Home W/ Heated Pool!
- Relaxing 4-Bedroom Home & Private Pool
- Private Pool & Hot Tub: Port St Lucie Escape Villa
- Chic 4Br Home Hot Tub Game Room
- Near Parks: Port St Lucie Home W/ Private Pool!
- Poolside Paradise
- 3 Bedrooms 2 Baths Pool Home Available For Longer Stays!!!
- A Home Where Memories Are Made
- Port Saint Lucie Getaway Villa
- Port Saint Lucie Vacation Rental W/ Hot Tub!
- Spacious Home Near Dtwn Psl: Travel Nurses Welcome
- Spacious Master Bedroom
- Massive 4 Bedroom Close To The Beach With A Pool
- Welcome To This Large Beautiful 3-Bedroom, 2-Bath
- Sea Lion Serenity Retreat - New Construction 2024
- Sandpiper Stay
- Pgavillageresort By Americanvacationliving 2 Br
- Port St Lucie Retreat: Lanai W/ Private Pool! Villa
- Mod Family Home W/ Outdoor Oasis: Near Pga Village
- Pool & River 2-Story Home
- White Sands Escape Solar Heated Pool & Fire Pit
- Outdoor Relaxation! Port St Lucie Family Home
- Heated Pool • Near Beach • Outdoor Dining + Gazebo
- Blue Skies Bungalow - Heated Pool & Beach Fire Pit
- Whispering Waters Villa
- Beach-Hop & Golf! Port St Lucie Apt W/ Shared Yard
- Family Home In Port St Lucie W/ Furnished Pergola!
- Gateway To St Lucie Villa
- Peace Of Mind And Resting Place
- 5 Mi To Boating! Port St Lucie Home With Backyard
- New 5 Star House With Pool & Heated Spa-Mins To Cleveland Clinic Tradition- Hca Hospital
- Wonderfull Oasis Villa
- Spacious And Centrally Located Port St Lucie Home!
- Sunshine Retreat - Heated Pool & Dock Ocean Access Villa
- Lomb Ct Villa
- Sharpe House Villa
- Beautiful In-Ground Pool Home
- Cozy 3Bed 2Bath Near Mets Stadium/Beach
- Spacious Backyard! Single-Level Port St Lucie Home
- Happy Place
- Bohemian Bungalow
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