Best-rated hotels in Big Pine Key for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

Check-in date:
Check-out date:
0 Adults

Adults

0 Children

Children

Apply

Why book with us?

Choose from exclusive hotel collection

We offer thousands of Big Pine Key hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

Enjoy seamless booking experience

Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.

Benefit from flexible travel options

We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

Find a hotel

Hotels by class
4 stars 1
3 stars 2
2 stars 1
Unrated 84
Accommodation type
Holiday homes 54
Holiday parks 19
Apartments 5
Bed & Breakfasts 3
Campsites 3
Motel 1
Homestay 1
Hotel 1
Lodge 1
Thematic Hotels
Vacation Rentals 36
Extended Stay 36
Cheap and budget hotels 27
Luxury accommodations 23
Pet-friendly hotels 18
Private Villas 15
Central hotels 8
Hotels with indoor pool 8
Beach hotels 8
Family Friendly hotels 8
Beachfront hotels 7
Jacuzzi 4
Spa hotels 1
Resorts 1
Self Catering 1
Business hotels 1
All Big Pine Key hotels

Hotels by location

Nearby
City Center Big Pine Key 1
Bahia Honda State Park 1
Big Pine Key Shopping Center 18
Landmarks
Parks
Landmark
Popular attractions
Florida >
Big Pine Key

Welcome to Big Pine Key

Discover the natural beauty of Big Pine Key, nestled in the heart of the Florida Keys. Immerse yourself in clear turquoise waters as you snorkel amongst vibrant coral reefs, or take a leisurely stroll along our pristine white sand beaches. Don't miss out on the chance to encounter our beloved Key deer who gracefully roam the island. Plan your visit to Big Pine Key today and experience the ultimate tropical getaway.

What our users say about Big Pine Key hotels

Floridays Orlando Two & Three Bed Rooms Condo Resort
9.8

Exceptional

us Sarah 14 January 2023
The accommodation is pet-friendly, well-equipped with spacious private bathrooms, and provides efficient service, even though some staff members may not be very helpful.
Read more +
Show Less -
The Grove Resort & Water Park Orlando
9.8

Exceptional

us Peter 07 June 2022
The hotel was hip new, had stunningly beautiful views and perfect location close to a water park and near by attractions and the center. I appreciated the room, the bed was comfy. There were a flat-screen TV with cable channels, climate control and a refrigerator. The staff was excellent, they made the stay good.
Read more +
Show Less -
Holiday Inn Resort Orlando Suites - Waterpark
9.8

Exceptional

us Willie 27 December 2022
Thanks very much all for an awesome stay during our visit.
Read more +
Show Less -
Best Western Orlando Gateway Hotel
9.8

Exceptional

us John 13 December 2022
The rooms and the staff here are top-notch. We were impressed by almost every little thing at this place! 😊
Read more +
Show Less -
Sandestin Golf And Beach Resort
9.8

Exceptional

us Brian 14 November 2022
The great location within walking distance of Alvin's Island and the luxurious room with extremely comfortable beds make this place a top choice for a relaxing stay.
Read more +
Show Less -
Buena Vista Suites Orlando
9.8

Exceptional

us Ian 14 September 2022
The rooms were clean and had a fantastic bathroom, located in a beautiful building in a convenient area close to the Bistro.
Read more +
Show Less -
Caribe Royale Orlando
9.8

Exceptional

us William 13 October 2022
I had a wonderful family vacation here, the staff was great, the rooms were nice, and the bed was super comfortable.
Read more +
Show Less -
DoubleTree by Hilton Hotel Orlando at SeaWorld
9.8

Exceptional

us Gregory 24 January 2022
Everything was perfect here - helpful staff and non-smoking rooms.
Read more +
Show Less -
Doubletree By Hilton At The Entrance To Universal Orlando
9.8

Exceptional

us Lisa 14 September 2022
The location was amazing, very close to Universal Studios, liquor stores, parks, restaurants. It was not too far from Trattoria del Porto; we ate there a couple of times.
Read more +
Show Less -
B Ocean Resort Fort Lauderdale Beach
9.8

Exceptional

us Paul 13 January 2023
Decent spot, quite tidy and cool. Liked it. Room was pretty clean and had a good view. 🌅
Read more +
Show Less -

Save time on your trip arrangements by booking one of our hand-picked hotels

Best 4-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Experience the best value for your money by checking out our selection of 4-star Big Pine Key hotels.
Beach View Room Barnacle Bed And Breakfast Deers Front Beach Suite

1557 Long Beach Drive, Big Pine Key, United States

458 US$

min. price/night

Enjoy truly authentic experiences without compromising comfort and convenience.
Deer Run On The Atlantic Bed & Breakfast

1997 Long Beach Road, Big Pine Key, United States

Excellent
5 reviews

517 US$

min. price/night

Barnacle Bed And Breakfast

1557 Long Beach Drive, Big Pine Key, United States

Average
5 reviews

413 US$

min. price/night

Discover the hidden gems of Big Pine Key by booking one of its budget-friendly hotels.
Sunshine Key Rv Resort & Marina

38801 Overseas Highway, Big Pine Key, United States

Excellent
91 reviews

245 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Big Pine Key Motel

30725 Overseas Highway

Good
514 reviews

169 US$

min. price/night

Old Wooden Bridge Resort & Marina

1791 Bogie Drive, Big Pine Key, United States

Good
318 reviews

149 US$

min. price/night

Ed & Ellen'S Canal Duplexes W/Dockage - Big Pine Key

1547 Narcissus Ave

Good
66 reviews

187 US$

min. price/night

Better Than A Tent

29859 Overseas Highway 10, Fl 33043, Big Pine Key, Us

Good
21 reviews

57 US$

min. price/night

Show less Show more

Thank you for your feedback

Close